Balloon angioplasty. A small balloon is inflated In the blocked artery to open up the blocked spot) Can peripheral artery disease be reversed? Atherosclerosis is the commonest explanation for PAD, and It's a buildup of plaque, or calcium, inside the arteries that causes blockage and does not disappear on its own. https://sgvasculargrp.com/medical-condition/peripheral-arterial-disease/