Below, we show that conolidine, a natural analgesic alkaloid used in regular Chinese drugs, targets ACKR3, thus providing additional evidence of a correlation concerning ACKR3 and ache modulation and opening substitute therapeutic avenues for the remedy of chronic discomfort. Though this research identifies the correlation amongst conolidine and ACKR3, https://larryv937qmg6.signalwiki.com/user