Greater activation of key oncogenic signalling pathways (PI3K/AKT, RAS/MAPK and MYC) upstream of ribosome biogenesis constitutes an extra hallmark of HGSC,9 and we hypothesise that inhibiting ribosome biogenesis can provide a successful cancer therapeutic alternative.ten In truth, We've revealed encouraging responses Using the ribosomal RNA gene (rDNA) transcription inhibitor CX-5461, https://stephent999rkc1.ageeksblog.com/profile