At this time, there are two forms of experiments on itaconate: Irg1−/− macrophages as well as regulatory effect of itaconate derivatives. Both of these benefits had been complementary and discovered which the regulatory mechanisms of itaconate included alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription aspect 3 https://lutherm776akv9.wikicommunication.com/user